EDITED BY
Drew Provan
Emeritus Reader in Autoimmune Haematology
Department of Haematology
Barts and The London School of Medicine and Dentistry
Queen Mary University of London
London
UK
This fourth edition first published 2018 © 2018 by John Wiley & Sons Ltd
Edition History
John Wiley & Sons Ltd (3e, 2009)
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Library of Congress Cataloging‐in‐Publication Data
Names: Provan, Drew, 1955– editor.
Title: ABC of clinical haematology / edited by Drew Provan.
Description: Fourth edition. | Hoboken, NJ : John Wiley & Sons, Inc., 2018. | Includes bibliographical references and index. |
Identifiers: LCCN 2017055360 (print) | LCCN 2017056756 (ebook) | ISBN 9781118892473 (pdf) | ISBN 9781118892480 (epub) | ISBN 9781118892343 (pbk.)
Subjects: | MESH: Hematologic Diseases–diagnosis | Hematologic Diseases–therapy | Hematologic Diseases–physiopathology
Classification: LCC RC633 (ebook) | LCC RC633 (print) | NLM WH 120 | DDC 616.1/5–dc23
LC record available at https://lccn.loc.gov/2017055360
Cover Design: Wiley
Cover Image: © Science Photo Library ‐ STEVE GSCHMEISSNER./Gettyimages
Katharine Bailey
Haematology, Cancer Institute, UCL, Royal Free Campus, London, UK
Catherine Booth
Specialist Registrar in Haematology, Barts and the London NHS Trust, London, UK
Richard Burt
Haematology, Cancer Institute, UCL, Royal Free Campus, London, UK
Tom Butler
Department of Clinical Haematology, Barts Health NHS Trust, Pathology & Pharmacy Building, Royal London Hospital, London, UK
Jenny L. Byrne
Nottingham University Hospitals NHS Trust, Nottingham, UK
Jamie Cavenagh
Consultant Haematologist, Department of Haemato‐Oncology, St Bartholomew’s Hospital, West Smithfield, London, UK
John de Vos
Consultant Haematologist, Royal Surrey County Hospital NHS Foundation Trust, Guildford, UK
Robin Dowse
Senior Specialist Registrar, Haematological Medicine, King’s College Hospital NHS Foundation Trust, Hambleden Wing, London, UK
Adele K. Fielding
Haematology, Cancer Institute, UCL, Royal Free Campus, London, UK
Anna L. Godfrey
Consultant Haematologist, Department of Haematology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
Anthony R. Green
Director, Wellcome Trust/MRC Cambridge Stem Cell Institute, University of Cambridge;
Department of Haematology, University of Cambridge, Cambridge, UK
Sandra Hassan
Consultant Haematologist, Queen’s Hospital, BHR NHS Trust, Romford, UK
Catherine Hockings
Department of Haematology, University College London Hospitals NHS Foundation Trust, London, UK
Victor Hoffbrand
Emeritus Professor of Haematology, University College London, London, UK
David M. Keeling
Consultant Haematologist, Oxford University Hospitals, Oxford Haemophilia & Thrombosis Centre, Churchill Hospital, Oxford, UK
R. J. Liesner
Director Haemophilia CCC, Great Ormond Street Hospital, London, UK
Christopher McNamara
Department of Haematology, University College London Hospitals NHS Foundation Trust, London, UK
Ghulam J. Mufti
Professor of Haemato‐oncology & Head of Department, Haematological Medicine, King’s College Hospital NHS Foundation Trust, Hambleden Wing, London, UK
Jim Murray
Haematology – University Hospitals Birmingham NHS Foundation Trust, Queen Elizabeth Hospital, Queen Elizabeth Medical Centre, Birmingham, UK
Adrian C. Newland
Barts and the London Medical School, Queen Mary University of London; Department of Clinical Haematology, Barts Health NHS Trust, Pathology & Pharmacy Building, Royal London Hospital, London, UK
Igor Novitzky‐Basso
Stem Cell Laboratory Medical Director, Queen Elizabeth University Hospital Glasgow, NHS Greater Glasgow and Clyde, Glasgow, UK
Drew Provan
Emeritus Reader in Autoimmune Haematology, Department of Haematology, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK
Marie A. Scully
Department of Haematology, University College London Hospitals NHS Trust, Cardiometabolic Programme‐NIHR UCLH/UCL BRC, London, UK
Julia Sikorska
Specialist Registrar in Haematology, Royal Surrey County Hospital NHS Foundation Trust, Guildford, UK
George S. Vassiliou
Group Leader and Consultant Haematologist, Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton;Wellcome Trust/MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK
David J. Weatherall
Regius Professor of Medicine Emeritus, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Headington, Oxford, UK