Details

Systems Biology of Cell Signaling


Systems Biology of Cell Signaling

Recurring Themes and Quantitative Models

von: James E. Ferrell

87,48 €

Verlag: Garland Science
Format: PDF
Veröffentl.: 28.09.2021
ISBN/EAN: 9781000430738
Sprache: englisch
Anzahl Seiten: 266

DRM-geschütztes eBook, Sie benötigen z.B. Adobe Digital Editions und eine Adobe ID zum Lesen.

Beschreibungen

How can we understand the complexity of genes, RNAs, and proteins and the associated regulatory networks? One approach is to look for recurring types of dynamical behavior. Mathematical models prove to be useful, especially models coming from theories of biochemical reactions such as ordinary differential equation models. Clever, careful experiments test these models and their basis in specific theories. This textbook aims to provide advanced students with the tools and insights needed to carry out studies of signal transduction drawing on modeling, theory, and experimentation. Early chapters summarize the basic building blocks of signaling systems: binding/dissociation, synthesis/destruction, and activation/inactivation. Subsequent chapters introduce various basic circuit devices: amplifiers, stabilizers, pulse generators, switches, stochastic spike generators, and oscillators. All chapters consistently use approaches and concepts from chemical kinetics and nonlinear dynamics, including rate-balance analysis, phase plane analysis, nullclines, linear stability analysis, stable nodes, saddles, unstable nodes, stable and unstable spirals, and bifurcations. This textbook seeks to provide quantitatively inclined biologists and biologically inclined physicists with the tools and insights needed to apply modeling and theory to interesting biological processes. Key Features: Full-color illustration program with diagrams to help illuminate the concepts Enables the reader to apply modeling and theory to the biological processes Further Reading for each chapter High-quality figures available for instructors to download

Diese Produkte könnten Sie auch interessieren:

Auftritt der Schatten
Auftritt der Schatten
von: Josephine Fenger
PDF ebook
23,20 €
Dialogue as a Means of Collective Communication
Dialogue as a Means of Collective Communication
von: Bela H. Banathy, Patrick M. Jenlink
PDF ebook
96,29 €
Malaria
Malaria
von: Krishna R. Dronamraju, Paolo Arese
PDF ebook
96,29 €